Home/Peptides/ACE-031 1mg
ACE-031 1mg
Body Composition
BODY COMPOSITION

Buy ACE-031 1mg

Myostatin inhibitor for dramatic lean mass gain and muscle preservation

Buy ACE-031 1mg — ACE-031 is an ActRIIB-Fc fusion protein that blocks myostatin and related TGF-β ligands, producing dramatic increases in lean muscle mass with concurrent fat loss.

  • Inhibits myostatin, activin A, and GDF-11 simultaneously
  • Produces 3–5% lean mass gains with single-dose clinical evidence
  • Concurrent reduction in fat mass for improved body composition
  • Preserves muscle mass during caloric restriction or illness
  • May improve bone mineral density via ActRIIB blockade
$179.99$199.99
10% OFF
COA Verified · Third-Party Tested
US Domestic Shipping
Buy ACE-031 1mg on Phiogen

COA verified · US domestic shipping

ACE-031: The ActRIIB Decoy Receptor That Clinically Doubled Muscle Growth Expectations

3–5% LBM in Weeks

Clinical trial data in DMD showed ACE-031 produced lean body mass increases of 3–5% within weeks of a single injection — unprecedented in muscle-building research.

Multi-Ligand Blockade

Blocks not just myostatin but also activin A and GDF-11 — all three ActRIIB ligands that suppress muscle growth, delivering more comprehensive inhibition than myostatin-only approaches.

Simultaneous Fat Loss

Clinical data confirmed concurrent fat mass reduction alongside lean mass gains — a dual body composition shift that is exceptionally difficult to achieve by any other means.

Bone Density Potential

ActRIIB signaling also regulates bone remodeling; ACE-031 blockade shows promise for increasing bone mineral density alongside its muscle effects.

The Science Behind ACE-031 1mg

Blocking the Muscle Growth Brake

ACE-031 (ACVR2B-Fc) is a fusion protein that acts as a decoy receptor for ActRIIB — the receptor through which myostatin, activin A, GDF-11, and other TGF-β family members signal to inhibit muscle growth. By binding these ligands before they reach their natural receptors, ACE-031 effectively removes the biological brakes on muscle hypertrophy, allowing dramatically accelerated muscle growth even without changes in training.

Clinical Evidence: Unprecedented Muscle Gains

In clinical trials for Duchenne muscular dystrophy, a single dose of ACE-031 produced 3–5% increases in lean body mass within weeks — results that typically require months of intense training. The compound simultaneously reduced fat mass, creating a highly favorable body composition shift. These results established ACE-031 as perhaps the most potent single-compound muscle-building agent in research.

Research and Athletic Applications

While developed for muscle-wasting diseases, ACE-031's mechanism is of intense research interest for body composition optimization. The multi-ligand inhibition (myostatin + activin A + GDF-11) distinguishes it from myostatin-only inhibitors, potentially explaining its superior potency. Research is also investigating its effects on bone density and cardiometabolic markers.

Complete ACE-031 1mg Benefits

  • Inhibits myostatin, activin A, and GDF-11 simultaneously
  • Produces 3–5% lean mass gains with single-dose clinical evidence
  • Concurrent reduction in fat mass for improved body composition
  • Preserves muscle mass during caloric restriction or illness
  • May improve bone mineral density via ActRIIB blockade
  • Potentially reverses muscle-wasting in disease states
  • Most potent lean mass agent studied in clinical trials

ACE-031 1mg Dosing Protocol

Reconstitution: Add 1mL bacteriostatic water (1,000mcg/mL).

Dosing:

Research protocol: 0.1–0.3mg/kg subcutaneous every 2–4 weeks

Note: ACE-031 is for research purposes only; clinical protocols vary by indication

Cycle: extended research cycles with careful monitoring

Caution: Potent compound — nose bleeds and vascular effects observed in trials at higher doses

All information on this site is for educational purposes only. Always consult with a qualified healthcare provider before use. COA documentation is available for all products.

ACE-031 1mg

COA verified · Third-party tested · US domestic shipping

Buy Now View Stack Protocols
Certificate of Analysis (COA)
US Domestic Shipping
COA-Verified Purity
24–48hr Processing
$179.99
$199.99
Body Composition

Body composition peptides optimize the GH/IGF-1 axis and metabolic signaling for simultaneous fat loss and muscle gain.

All Body Composition Peptides

Stack ACE-031 1mg With

TB-500Healing

TB-500

Systemic Body-Wide Repair & Flexibility

TB-500 For Sale — TB-500 (Thymosin Beta-4) provides systemic healing — mobilizes stem cells, repairs muscles and tendons simultaneously, and dramatically improves flexibility.

healing flexibility muscle
$53.99$59.99
Buy Now
NAD+ 100mgHealing

NAD+ 100mg

Injectable NAD+ for cellular energy, DNA repair, and anti-aging restoration

Verified NAD+ 100mg — Injectable NAD+ 100mg — the coenzyme central to cellular energy metabolism, sirtuin activation, DNA repair, and mitochondrial biogenesis for comprehensive anti-aging support.

NAD+ Anti-Aging Energy
$26.99$29.99
Buy Now
Ipamorelin 10mgBody Composition

Ipamorelin 10mg

Selective GHRP for clean GH release without cortisol or prolactin elevation

Buy Ipamorelin 10mg — Ipamorelin is a selective growth hormone releasing peptide (GHRP) that stimulates pulsatile GH release with minimal cortisol, prolactin, or acetylcholine side effects.

Ipamorelin GHRP Growth Hormone
$53.99$59.99
Buy Now